140.688 Bioinformatics and Computational Biology Solutions Using R and Bioconductor

Graph plotting percentage trends over time
Course

Instructor

Rafael Irizarry

Originally Offered

Spring 2006

Offered By

Biostatistics


Description

Covers the basics of R software and the key capabilities of the Bioconductor project (a widely used open source and open development software project for the analysis and comprehension of data arising from high-throughput experimentation in genomics and molecular biology and rooted in the open source statistical computing environment R), including importation and preprocessing of high-throughput data from microarrays and other platforms. Also introduces statistical concepts and tools necessary to interpret and critically evaluate the bioinformatics and computational biology literature. Includes an overview of of preprocessing and normalization, statistical inference, multiple comparison corrections, Bayesian Inference in the context of multiple comparisons, clustering, and classification/machine learning.


OCW offers a snapshot of the educational content offered by JHSPH. OCW materials are not for credit towards any degrees or certificates offered by the Johns Hopkins Bloomberg School of Public Health.

For information on for-credit courses go to: http://commprojects.jhsph.edu/courses. Unlike for-credit courses, OpenCourseWare does not require registration and does not provide access to the School's faculty.