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Readings
Textbook
Essentials of Toxicology. Klaassen CD, Watkins JB III, eds. New York: McGraw-Hill, 2003.
| TOPIC | READINGS |
|---|---|
|
Module 1: General Principles
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| Lecture 1: Absorption, Distribution, and Excretion |
Casarett and Doull's Essentials of Toxicology pages 22-26, 59-70, 98-107, and 209-211. |
| Lecture 2: Xenobiotic Biotransformation |
Casarett and Doull's Essentials of Toxicology pages 72-74, 77-97, and 25-28. |
| Lecture 3: Environmental Carcinogenesis |
Casarett and Doull's Essentials of Toxicology Chapter 8: Chemical Carcinogenesis pages 111-130 Chapter 9: Genetic Toxicology pages 131-145 |
| Lecture 4: Cancer Biomarkers & Susceptibility Factors |
Perera FP. Uncovering new clues to cancer risk. Scientific American 1996;274:54. |
| Lecture 5: Elements of Risk Assessment |
Casarett and Doull's Essentials of Toxicology Chapters 2, 4, 34, and self-assessment questions Toxicity Testing for Assessment of Environmental Agents - Interim Report. National Research Council of the National Academies, Washington DC, 2006. Toxicity Testing in the Twenty-first Century: A vision and a Strategy. National Research Council of the National Academies, Washington DC, 2007. |
|
Module
2: Case Studies
|
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| Lecture 6: Hepato & Renal Toxicology |
Casarett and Doull's Essentials of Toxicology Hepatotoxicity, Chapter 13 Renal Toxicity, Chapter 14 |
| Lecture 7: Reproductive and Developmental Toxicology |
Casarett and Doull's Essentials of Toxicology Chapters 10 and 20 |
| Lecture 8: Persistent Organic Pollutants (POPs) and Dioxins |
Casarett and Doull's Essentials of Toxicology pages 343, 297-298, and 336-338 (organochlorine compounds) |
| Lecture 9: Neurotoxicology |
Casarett and Doull's Essentials of Toxicology Chapter 16 |
| Lecture 10: Immunotoxicology |
Casarett and Doull's Essentials of Toxicology pages 176-193 and 291-293. |
| Lecture 11: Air Toxicants |
Casarett and Doull's Essentials of Toxicology pages 220-232 and 407-418. |
| Lecture 12: Food-Borne Toxicants and Prevention in Toxicology |
Casarett and Doull's Essentials of Toxicology Chapter 30: Food Toxicology, pages 431-439 Kensler T, et al: Translational strategies for cancer prevention in liver. Nature Reviews Cancer. 2003;3:321-329. |
| Lecture 13: Metal Toxicology |
Casarett and Doull's Essentials of Toxicology pages 348-353 and 355-356 |
