Course: Animals in Research: Law, Policy, and Humane Sciences

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Readings

Most of these materials as well as many others are also available through Altweb and CAAT: The Center for Alternative to Animal Testing.


Topic Readings
Session 0: Introduction and Overview Center for Alternatives to Animal Testing
Session 1: 3Rs and Humane Science

Goldberg AM, Hartung T. Protecting more than animals. Scientific American January 2006: 84-91

Gawrylewski A. The trouble with animal models. The Scientist 2006;21:44

Festig S. Animal Experimentation: The Need for Deliberation and Challenge. ATLA 2008;36:1-4

Locke, P., Goldberg, A.M., Chapter 10 in "Toxicology and the Regulatory Process: Alternatives to Animals in Toxicology," Sidney Green (ed), Taylor & Francis 2006

Goldberg AM, Locke PA. To 3R is humane. The Environmental Forum. 2004:18-26

Gardner RM, Goldberg AM. Pain-free animals: An acceptable alternative? Proceedings of the 6th World Congress on Alternatives & Animal Use in the Life Sciences. Tokyo, Japan. March 31, 2008.

AltWeb from the Center for Alternatives to Animal Testing

Russell WMS, Burch RL. The Principles of Humane Experimental Technique.

Committee on Toxicity Testing and Assessment of Environmental Agents, National Research Council. Toxicity Testing in the 21st Century: A Vision and a Strategy. Washington DC: The National Academies Press, 2007.

Online Humane Science Course

Session 2: Legal and Policy Issues in Humane Science: Where Have We Been, Where Are We Now, and Where Are We Going?

Goldberg AM, Spielmann H. High production volume (HPV) chemical testing. In: M. Balls, et al., eds. Progress in the Reduction, Refinement and Replacement of Animal Experimentation. Philadelphia: Elsevier. 2000

Green S, Goldbert AM, Zurlo J. TestSmart-high production volume chemicals: An approach to implementating alternatives into regulatory toxicology. Toxicological Sciences 2001;63:6-14

US vs. Catholic Healthcare West. United States Court of Appeals for the Ninth Circuit. Filed April 19, 2006

Nuffield Council on Bioethics. The ethics of research involving animals. London: Nuffield Council on Bioethics, 2005

Eigo T. Laws for paws: A new breed of law section. Arizona Attorney, December 2005

Sunstein CR. The rights of animals: A very short primer. Public Law and Legal Theory Working Paper No. 30. The Law School of the University of Chicago

US Animal Welfare Act

Federal Insecticide, Fungicide, and Rodenticide Act

Toxic Substances Control Act

ICCVAM Authorization Act of 2000

Session 3: Institutional Animal Care and Use Committees: An Overview

Schuppli CA, Fraser D, McDonald M. Expanding the three Rs to meet new challenges in humane animal experimentation. ATLA 2004;32:525-532

Office of Laboratory Animal Welfare. Institutional Animal Care and Use Committee, 2nd Edition. 2002

Session 4: Ethical Issues in Research

Emmanuel EJ, Wendler D, Grady C. What makes clinical research ethical? JAMA 2000;283:2701-2711

The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. The Belmont Report: Ethical principles and guidelines for the protection of human subjects in research. The National Institutes of Health.

Session 5: International Issues in Humane Science

7th Amendment to the Cosmetics Directive in the EU. 27 February 2003

Canadian Council on Animal Care

European Union REACH Legislation

Animal Memorial Service, Tokyo, Japan

Alternatives to Animal Testing - In Song

Session 6: Refinement Issues in Animal Research No Reading Required
Session 7: The Compelling Case for Rigorous Training Requirements No Reading Required
Session 8: Wrap-up No Reading Required