Course: Methods in Biostatistics II
Schedule
Session  Topic  Activities 

15 
Hypothesis Testing 1. Introduce hypothesis testing 
Read Rosner Chapt 7.17.7 
16 
Power and sample size and two group tests 1. Power 
Read Rosner 8.18.8 and 8.108.12 
17 
Power and sample size and two group tests 1. Paired difference hypothesis tests 
Read Rosner 8.18.8 and 8.108.12 
18 
Tests for binomial proportions 1. Tests for a binomial proportion 
Read Rosner 7.10 
19 
Two sample binomial tests, delta method 1. Define relative risk 
Read Rosner 10.1, 10.2, 13.113.3 
20 
Two sample binomial tests, delta method 1. Review two sample binomial results 

21 
Fisher's exact tests, Chisquared tests 1. Introduce Fisher's exact test 
Read Rosner 10.2, 10.3, 10.610.9 
22 
Fisher's exact tests, Chisquared tests 1. Chisquared tests for equivalence of two binomial proportions 
Multinomial Distribution Notes Read Rosner 10.2, 10.3, 10.610.9 
23 
Simpson's pardox, confounding 1. Simpson's paradox 
Read Rosner 13.4 & 13.5 
24 
Retrospective casecontrol studies, exact inference for the odds ratio 1. Odds ratios for retrospective studies 

25 
Methods for matched pairs, McNemar's, conditional versus marginal odds ratios 1. Hypothesis tests of marginal homgeneity 
Read Rosner 10.4 
26 
Nonparametric tests, permutation tests 1. Distributionfree tests 

27 
Inference for Poisson counts 1. Poisson distribution 

28 
Multiplicity 1. Familywise error rates 