Course: Public Health Toxicology

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Readings

There is no required text. However, there are assigned readings for each lecture that are accessed through e-reserves.

Excellent reference texts for those who want more detailed information are:

  • Casarett and Doull’s  Essentials of Toxicology,  8th (or earlier) edition, C.D. Klaassen and J.B. Watkins III, eds. McGraw Hill Medical, NY, 2013. 
  • Principles and Methods of Toxicology. Fifth Edition. A. Wallace Hayes (ed). CRC Press, Boca Ratan, 2008. (Older editions also contain basic information that may be helpful.)

Session Topic Readings
Lecture 1 Introduction to Basic Principles Chap1, pgs 1-3; Chap 2, pp 5-7; Chap 3, pp 21-44
Lecture 2 Toxicokinetics: Absorption, Distribution, Excretion Chap 5, pgs57-68; Chap 19, pp 269-270
Lecture 3 Toxicokinetics : Biotransformation Chap 6, pp 71-72, 86-87,89,95,96
Lecture 4 Testing, dose response, risk assessment

Chapter 2, pp 9-17, Chapter 4, Chapter 8, pp 117-118

Lecture 5 Environmental carcinogenesis Chapters 8 & 9, pp 123-129, 132-133 (human population monitoring)
Lecture 6 Biomarkers of exposure, effect and susceptibility factors Chapter 24, pp 338
Lecture 7 Approaches to primary and secondary prevention in toxicology Chapter 3, pp 22-24